Inverse Mapping of Spatial-Temporal Molecular Heterogeneity from Imaging Phenotype

Oct 21, 2020 | AI in medicine and imaging

Sponsor NSF A significant challenge in treating some aggressive cancers and neurological diseases is the lack of understanding regarding the spatial-temporal molecular heterogeneity of the diseased tissue/organ. Molecular characteristics and interaction vary...

Imaging the migraine brain pre-and post-erenumab: an MRI study

Oct 21, 2020 | AI in medicine and imaging

Sponsor: Amgen Inc. This study will investigate longitudinal changes in brain structure and function in high frequency episodic and chronic migraine patients who are responding to erenumab treatment compared to those patients who are non-responders. In addition,...

Noninvasive MRI techniques to detect pathology in murine models of renal disease

Oct 21, 2020 | AI in medicine and imaging

Sponsor: DOD The broad, long-term goal of this multi-disciplinary collaborative of biomedical engineers and physician- scientists is to develop early, non-invasive methods to identify individuals at risk of developing chronic kidney disease (CKD). Current methods to...

A multidisciplinary translational approach to investigate the mechanisms, predictors, and prevention of persistent post-traumatic headache

Oct 21, 2020 | AI in medicine and imaging

Sponsor: DOD Post-traumatic headache (PTH) is the most common symptom following mild traumatic brain injury (mTBI). Some PTHs resolve within the first few days of onset, even without any specific treatment. However, in a large proportion of individuals the PTHs do not...